Hematopoietic Stem Cell Transplantation (by LabCE)

1.5 P.A.C.E. contact hour(s)

(based on 197 customer ratings)

Author: David M. Falleur, M.Ed., MT(ASCP)
Reviewer: Leah Coppolino, MPH, MLS(ASCP)

Course provided by LabCE.

Hematopoietic stem cell (HSC) transplantation has become a procedure that offers hope to many patients with cancer and other life-threatening diseases. This course aims to provide information about the importance of HSC transplantation and the role played by the clinical laboratory in HSC collection, processing, administration, and the patient's ongoing care after transplant. The sources of HSCs used in transplants, their application in the treatment of malignant and nonmalignant disorders, and the complications associated with HSC transplantation are also discussed.

See more courses in: Hematology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1.5 hour(s)
Course number 578-009-17, approved through 2/28/2019
Course number 20-563607, approved through 9/1/2020

Objectives

  • Identify the three sources of hematopoietic stem cells (HSCs).
  • Describe the appropriate use of umbilical cord, bone marrow, and peripheral stem cells in the treatment of malignant and nonmalignant disorders.
  • Describe the role of the clinical laboratory in HSC collection, processing, administration, and patient care following transplantation.
  • Recognize complications associated with HSC transplantation and procedures to prevent or minimize them.
  • Support the National Marrow Donor Registry and their "Be the Match" campaign by providing information to the laboratory community and the general public about the importance of HSC transplantation.

Customer Ratings

(based on 197 customer ratings)

Course Outline

  • Overview and History
      • Overview and History
  • Hematopoietic Stem Cells
      • Hematopoietic Stem Cells (HSCs)
      • Progenitor Cells
      • Important Definitions
  • Sources of Hematopoietic Stem Cells
      • Sources of Hematopoietic Stem Cells: Bone Marrow
      • Sources of Hematopoietic Stem Cells: Peripheral Blood
      • Sources of Hematopoietic Stem Cells: Umbilical Cord Blood
  • Preservation and Infusion of HSCs
      • Preservation and Infusion of HSCs
  • Human Leukocyte Antigen Testing for HSC Transplantation
      • Human Leukocyte Antigens (HLAs) and HSC Transplantation
      • Donor and Recipient Testing of Human Leukocyte Antigens (HLAs)
  • Recruiting and Matching Donors with Patients
      • Finding Donors for Transplant Patients
      • Donor Requirements and Testing
      • Matching Donors with Transplant Recipients
  • Preparing the Patient for Transplant
      • Preparing the Patient for Transplant
  • Hematopoietic Diseases Treatable by HSCs
      • Treatment of Hematologic Diseases by HSC Transplantation
  • Nonhematopoietic Diseases Treated by HSCs
      • HSC Transplants for Nonhematologic Diseases
  • Complications of HSC Transplantation
      • Graft versus Host Disease
      • Graft Failure
      • Relapse
      • Infection
      • Late Effects After HSC Transplantation
      • ABO Incompatibility in HSC Transplants
      • Graft Versus Tumor Effect
  • Acknowledgements
      • Acknowledgements
  • References
      • References

Additional Information

Level of Instruction: Beginning to intermediate

Intended audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for clinical laboratory science students and pathology residents.

Author information: David Falleur, M.Ed, MT(ASCP) is an Associate Professor in the Clinical Laboratory Science Program at Texas State University in San Marcos, Texas. David has more than 40 years of teaching experience in hematology and clinical chemistry. David has been active at the national level serving as Annual Meeting Chair for the ASCLS Annual Meeting in 2015 and at the state level as President of the Texas Association for Clinical Laboratory Science.

Reviewer information: Leah Coppolino, MPH, MLS(ASCP) is a Program Director for MediaLab, Inc. Leah was previously the Director of the Medical Laboratory Science Program at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania. She holds a Masters in Public Health from Thomas Jefferson University.

Course description: Hematopoietic stem cell (HSC) transplantation has become a procedure that offers hope to many patients with cancer and other life-threatening diseases. This course aims to provide information about the importance of HSC transplantation and the role played by the clinical laboratory in HSC collection, processing, administration, and the patient's ongoing care after transplant. The sources of HSCs used in transplants, their application in the treatment of malignant and nonmalignant disorders, and the complications associated with HSC transplantation are also discussed. 

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