White Cell and Platelet Disorders: Peripheral Blood Clues to Nonneoplastic Conditions (by LabCE)

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s) Course number 578-049-16, approved through 6/30/2018

Florida Board of Clinical Laboratory Personnel Credit Hours - General (Hematology): 2 hour(s) Course number 20-547973, approved through 9/1/2018

Objectives

• Recognize several peripheral white cell abnormalities and list the criteria necessary to request a morphological/clinical review.
• Recognize and list the criteria by which a leukemoid reaction is differentiated from leukocytosis with a left shift.
• Describe various intracellular white blood cell inclusions and correlate them with the metabolic, genetic, and reactive conditions with which they are associated.
• Estimate platelet counts from peripheral blood smear scans and discuss erroneous automated platelet results.

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Course Outline

• White Blood Cell Disorders and Platelets:
• Peripheral Smear Review Introduction
• Peripheral Blood Smear Preparation
• Evaluation Criteria: White Blood Cells and Platelets
• Criteria for Performing a Manual Review of the Smear
• Platelet Estimates
• Additional Comments
• Leukemoid Reaction and Toxic Changes
• Leukemoid Reaction
• Toxic Changes
• Thrombocytosis Associated with Toxic Granulation
• Case Study One
• White Cell Nuclear and Cytoplasmic Abnormalities Related to Inherited Conditions
• Pelger-Huet Anomaly
• Chediak-Higashi Anomaly
• Alder Anomaly
• May-Hegglin Anomaly
• WBC inclusions: Summary
• Familial disorders: summary
• Case Study Two: Follow-up
• 5. Miscellaneous Granulocytic Cells
• Eosinophils
• Basophils
• 6. Non Granulocytic White Blood Cells
• Disorders and Diseases Associated With Increased Monocytes
• Case Study Three
• Case Study Four
• Case Study Five
• Multiple Myeloma
• Smudge Cells
• 7. Platelets
• Giant Platelets
• Thrombocytopenia
• Pseudo-thrombocytopenia
• Thrombocytosis
• References
• References

Additional Information

Level of instruction: Intermediate

Intended Audience: Medical laboratory professionals, clinical laboratory science students and instructors of hematology.

General Information: This program provides several outstanding interactive case studies, which cover pertinent topics in white cell and platelet disorders. Numerous excellent photomicrographs enhance the text, and interactive questions help the student master the material.

Author Credentials: C. William Reiquam M.D. is a clinical pathologist at University of Colorado Health Sciences in Denver, CO. He has extensive experience in hematology and is currently focusing on evidence-based medicine and its implication for medial care outcomes.

Elmer W.Koneman M.D. is Professor Emeritus, Department of Pathology, University of Colorado School of Medicine. Residing in Breckenridge,CO, Dr. Koneman is a Board Certified Pathologist, former full Professor of Pathology University of Colorado School of Medicine. He is author of numerous journal articles and books.