ABO Typing Discrepancies (by ASCLS)

This course does not carry any current continuing education credits.

(based on 25 customer ratings)

Nicole Draper, MD, Asst. Medical Director, Transfusion Services, University of Colorado Hospital

Course provided by ASCLS.

Discrepancies in ABO typing lead to delays in determination of products that are safe to transfuse to the patient. When the ABO type has not clearly been determined, transfusion of universal donor red cells and plasma are necessary, thus depleting the supply of these products. It is important to know the possible causes of ABO discrepancies in order to develop algorithms and standard procedures to resolve them quickly. This self-study will provide a general scheme for resolving ABO discrepancies and work through examples cases.

See more courses in: Blood Banking / Immunohematology

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Objectives

  • Identify the most likely causes of an ABO discrepancy.
  • Describe the additional testing necessary to resolve the discrepancy.
  • List what products are safe to transfuse until the discrepancy is resolved.

Customer Ratings

(based on 25 customer ratings)

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Course Outline

  • PowerPoint Slides
      • ABO Typing Discrepancies
      • Learning Objectives
      • ABO Blood Group Antigens
      • ABO Antibodies
      • ABO Antigens and Antibodies
      • ABO Typing
      • RBC Compatibility
      • Plasma Compatibility
      • Frequency
      • Case 1 - Automated Testing
      • Case 1- Automated Testing & Tube Testing
      • Case 1 - Automated & Tube Testing, cont.
      • Lectin - Dolichos biflorus
      • Case 1
      • Transfusion
      • Case 2 - Automated Testing
      • Case 2 - Automated & Tube Testing
      • Case 2 - Automated & Tube Testing, cont.
      • Case 2 - History
      • A-Subgroups
      • Transfusion
      • Case 3 - Automated Testing
      • Case 3 - Automated & Tube Testing
      • Case 3 - History
      • Transfusion
      • Case 4 - Automated & Tube Testing
      • Case 4 - Automated & Tube Testing, cont.
      • Case 4 - Transfusion?
      • Antibody Panel
      • Case 4: anti-M
      • Case 4 - Transfuse?
      • Gain of Antibody
      • Case 5- Automated Testing
      • Case 5 - History
      • Case 5 - Retype and Transfuse
      • Case 6 - Automated Testing
      • Case 6 - History
      • Case 6 - Automated & Tube Testing
      • Mixed Field Agglutination
      • Case 6, cont.
      • Gain of Antigen
      • Case 7- Automated Testing
      • Case 7- History
      • Case 7 - Tube Testing
      • Loss of Antibody
      • Case 8- Tube Testing & History
      • Case 8, cont.
      • Case 8 - Antigen Enhancement
      • Case 8 - Typing for Patient & Mother
      • Loss of Antigen
      • Summary
      • References

Additional Information

Discrepancies in ABO typing lead to delays in determination of products that are safe to transfuse to the patient. When the ABO type has not clearly been determined, transfusion of universal donor red cells and plasma are necessary, thus depleting the supply of these products. It is important to know the possible causes of ABO discrepancies in order to develop algorithms and standard procedures to resolve them quickly. This self-study will provide a general scheme for resolving ABO discrepancies and work through examples cases.

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Blood Banking Course Package (4.5 hours) (by ASCLS)
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Course provided by ASCLS.
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