Corynebacterium and their Importance in Infections (by LabCE)

2 P.A.C.E. contact hour(s)

(based on 1,296 customer ratings)

Author: Jennifer Eddins PhD, SM(ASCP); Reviewer: Erin Phipps M(ASCP)

Course provided by LabCE.

Medical Laboratory Scientists responsible for reporting microbiology culture results should be aware that Corynebacterium species and similar organisms recovered from clinical specimens have the potential to be pathogenic. This course provides an overview of some of the common Corynebacterium species that have been shown to cause human diseases, along with primary sources and modes of infections. This course also highlights biochemical reactions, other testing methods for identification, susceptibility, treatment options, and a brief overview of potentially pathogenic organisms that could be mistaken for Corynebacterium species.

See more courses in: Microbiology

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-006-22, approved through 1/31/2024
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Microbiology/Mycology/Parasitology): 2 hour(s)
Course number 20-895814, approved through 1/31/2024

Objectives

  • Discuss the history and general characteristics of Corynebacterium species.
  • Discuss species shown to cause infections.
  • List primary sources and modes of infections.
  • Explain traditional biochemical testing, current testing using mass spectrometry (Maldi-TOF), and other methods.
  • Discuss susceptibility testing options and treatment recommendations.
  • Describe organisms that can be mistaken for Corynebacterium species.

Customer Ratings

(based on 1,296 customer ratings)

Course Outline

  • History and general characteristics of Corynebacterium species.
      • General Characteristics
      • History
      • Diphtheria
      • Emerging Pathogenicity
  • Species shown to cause infections
      • Corynebacterium accolens
      • Corynebacterium amycolatum
      • Corynebacterium jeikeium
      • Corynebacterium kroppenstedtii
      • Corynebacterium macginleyi
      • Corynebacterium minutissimum
      • Corynebacterium propinquum
      • Corynebacterium pseudotuberculosis
      • Corynebacterium riegelii
      • Corynebacterium striatum
      • Corynebacterium tuberculostearicum
      • Corynebacterium ulcerans
      • Corynebacterium urealyticum
      • Corynebacterium xerosis
      • Black colony Corynebacterium species
  • Primary sources and modes of infection
      • Infection Sites Related to Species
      • Modes of Transmission
      • Types of Infections
      • Distinguishing Between Infections, Colonization, and Contamination
      • Blood, Urine, and Respiratory Considerations
      • Corynebacterium's Role in Polymicrobial Infections
  • Traditional biochemical reactions, current testing using Maldi-TOF identifications, and other methods.
      • Biochemical Characteristics
      • Biochemical and Other Testing Methods
      • Biochemical Reactions To Distinguish Corynebacterium that Can be Found in Upper Respiratory Tract in Humans
      • Useful Biochemical Properties of Corynebacterium To Distinguish Between Some Additional Isolates
      • Matrix-Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF)
      • Alternative Methods for Identification: DNA Sequencing
      • Alternative Methods for Identification: PCR
  • Susceptibility testing
      • Susceptibility Methods
      • Susceptibility Methods, continued
      • Susceptibility Testing for Corynebacterium
      • Susceptibility for Other Coryneform Bacteria
      • Known Resistance Patterns
      • Resistance Mechanisms
  • Treatment options
      • Antimicrobial Resistance
      • Recommended Antibiotics Mode of Action
      • Additional Treatment Options
      • Immunotherapy and Other Treatment Options
      • Treatment Based Upon Species
  • Corynebacterium look-alikes
      • Coryneform-Like Organisms
      • General Characteristics of Corynebacterium species and Coryneform-Like Organisms
      • Non-Coryneform Gram-Positive Rods and Possible Look-Alikes
      • Changing Ecology and Pathogenicity
  • References
      • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: This course is intended for all laboratory personnel. This course is also appropriate for clinical laboratory science students and pathology residents.
Author Information: Jennifer Eddins PhD, SM(ASCP) has over 30 years of experience in medical microbiology as a technologist, lead, and technical specialist. She also teaches introductory microbiology courses online to pre-nursing students and creates continuing education modules for MediaLab. Jennifer has a BS in Microbiology from Colorado State University and a PhD in Public Health with a focus on epidemiology from Walden University.
Reviewer Information: Erin Phipps, M(ASCP), has 20 years of experience as a medical laboratory scientist. She is currently a Lead Medical Lab Scientist in the Molecular Diagnostics Department at the University of Colorado Hospital.
Course Description: Medical Laboratory Scientists responsible for reporting microbiology culture results should be aware that Corynebacterium species and similar organisms recovered from clinical specimens have the potential to be pathogenic. This course provides an overview of some of the common Corynebacterium species that have been shown to cause human diseases, along with primary sources and modes of infections. This course also highlights biochemical reactions, other testing methods for identification, susceptibility, treatment options, and a brief overview of potentially pathogenic organisms that could be mistaken for Corynebacterium species.

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Course provided by LabCE.
Corynebacterium accolens Blood agar plate image (5)


Corynebacterium amycolatum Gram stain image (6)


Corynebacterium minutissimum under Wood's lamp image (9)


Corynebacterium propinquum Gram stain image (10)


C. pseudotuberculosis Gram stain image (1)



 
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