1 P.A.C.E. contact hour(s)

(based on 405 customer ratings)

Course provided by LabCE.

See more courses in: Microbiology

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-086-20, approved through 8/31/2022
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Microbiology/Mycology/Parasitology): 1 hour(s)
Course number 20-788450, approved through 9/1/2022


  • Differentiate between prion proteins and prions.
  • Discuss the function of prion proteins and explain how prions effectuate several neurodegenerative diseases.
  • List several theories advocating causes for prion infections.
  • Discuss the causes and symptoms of the four types of infectious prion diseases and four types of classical prion diseases.
  • Restate the World Health Organization’s clinical laboratory recommendations for the handling of blood and body fluid specimens from individuals infected with prion diseases.

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(based on 405 customer ratings)

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Course Outline

  • What are Prions?
      • Prion Proteins
      • Prions
      • Transmissible Spongiform Encephalopathies (TSEs)
  • Theories Regarding Prion Infection
      • Research
      • Theories
      • Hypothesis
      • Multi-component Hypothesis
  • Symptoms and Histopathology of Prion Disease
      • How do prions kill?
      • Hypotheses and Theories on the Killing Mechanisms of Prions
      • Amyloid Fibers and Glial Cells
      • Signs and Symptoms of Prion Disease
      • Summary of Both Human and Non-human Prion Disease Forms: Major Neuropathological Features and Etiology
  • Infectious Prion Diseases
      • Kuru
      • Clinical Presentation: Kuru
      • Scrapie
      • Clinical Presentation: Scrapie
      • Bovine Spongiform Encephalopathy (BSE)/Mad Cow Disease
      • Bovine Spongiform Encephalopathy (BSE)/Mad Cow Disease: Statistics
      • Variant Creutzfeldt-Jakob Disease (vCJD): Clinical Presentation and Relationship to Bovine Spongiform Encephalopathy (BSE)
      • Variant Creutzfeldt-Jakob Disease (vCJD): Statistics and Prevention
      • Variant Creutzfeldt-Jakob Disease (vCJD): Safeguards
  • Other Human Prion Diseases
      • Creutzfeldt-Jakob Disease (CJD)
      • Creutzfeldt-Jakob Disease (CJD): Sporadic Versus Iatrogenic
      • Fatal Familial Insomnia (FFI)
      • Fatal Familial Insomnia (FFI): Clinical Presentation
      • Gerstmann-Sträussler-Scheinker Disease (GSS)
      • Prion Diseases and Prion Concentration
  • Laboratory Safety
      • Safety Precautions
      • Infection Control Strategies
      • Autopsy in Suspected or Known Cases of Prion Disease
  • Diagnosis
      • Diagnosis
  • References
      • References
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