Immune Hemolytic Anemias (by LabCE)

2 P.A.C.E. contact hour(s)

(based on 661 customer ratings)

Author: Erin Tretter, MBA, MT(ASCP)
Reviewer: Kathy W. Jones, MS, MLS(ASCP)CM

Course provided by LabCE.

See more courses in: Blood Banking / Immunohematology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-013-18, approved through 6/30/2020
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Blood Banking / Immunohematology): 2 hour(s)
Course number 20-659548, approved through 9/1/2020

Objectives

  • Compare the different types of immune hemolytic anemias.
  • Identify and investigate potential serologic discrepancies caused by autoimmune and drug-induced hemolytic anemias.
  • Differentiate the four mechanisms involved in drug-induced hemolytic anemias.
  • List medications that may be associated with drug-induced hemolytic anemia.

Customer Ratings

(based on 661 customer ratings)

Course Outline

  • Immune Hemolytic Anemias
      • Introduction
      • Direct Antiglobulin Test (DAT)
      • Classification of Hemolytic Anemias
  • Alloimmune Hemolytic Anemia
      • Alloimmune Hemolytic Anemia
  • Autoimmune Hemolytic Anemias
      • Autoimmune Hemolytic Anemia (AIHA): Introduction
      • Symptoms of Autoimmune Hemolytic Anemias
      • Testing for Autoantibodies
      • Possible Serological and Laboratory Presentations
    • Cold Autoimmune Hemolytic Anemia
      • Cold Autoimmune Hemolytic Anemia
      • Cold Hemagglutinin Disease (CHD)
      • Paroxysmal Cold Hemoglobinuria (PCH)
      • PCH Donath-Landsteiner Test
      • ABO/Rh Typing in the Presence of Cold Autoantibodies
      • Laboratory Presentations of Cold Autoantibodies - Antibody ID and Detection
    • Warm Autoimmune Hemolytic Anemia
      • Warm Autoimmune Hemolytic Anemia (WAIHA)
      • Serological Characteristics in WAIHA
      • WAIHA Investigation: Serological Findings Following Elution
      • Possible Scenarios When Transfusions are Needed in the Presence of WAIHA
      • Detection and Identification of An Alloantibody in the Presence of a Warm-Reactive Autoantibody
      • Autologous Adsorption (Autoadsorption)
      • Allogeneic Adsorption
      • Transfusion Considerations for WAIHA
      • Treatment of WAIHA
    • Mixed-Type Autoimmune Hemolytic Anemia
      • Mixed Type Autoimmune Hemolytic Anemia (AIHA)
  • Drug-Induced Hemolytic Anemia
      • Drug-Induced Immune Hemolytic Anemia Introduction
      • Mechanisms
      • Drug Adsorption Mechanism
      • Immune Complex Mechanism
      • Membrane Modification (Non-Immune Adsorption of Proteins)
      • Induction of Autoimmunity
      • Treatment of Drug-Induced Immune Hemolytic Anemia
      • Laboratory Investigation of Drug-Induced Immune Hemolytic Anemia
  • Case Study
      • Case Study One, continued
      • Case Study One, continued
      • Case Study One, continued
      • Case Study One Conclusion
  • Case Study
      • Case Study Two
      • Case Study Two, continued
      • Case Study Two, Conclusion
  • References
      • References

Additional Information

Author information: Erin Tretter, MBA, MT(ASCP), is currently the Rapid Response Laboratory Supervisor at Paoli Hospital. Erin received her Masters in Business Administration from Florida Institute of Technology where she is a member of the Phi Kappa Phi Honor’s Society. She received her BS in Medical Technology from California University of Pennsylvania and has experience as a Generalist, including Blood Bank, Hematology and Chemistry. Erin is currently the Blood Bank Clinical Instructor for the Clinical Laboratory Science Program at St. Christopher’s Hospital for Children and has 7 years experience teaching immunohematology concepts and laboratory procedures to laboratory science students. She has also taught Blood Bank in the Clinical Laboratory Technician program at the Community College of Philadelphia.
Reviewer information: Kathy W. Jones, MS, MLS(ASCP)CM is currently an Associate Professor in the Medical Laboratory Science Program at Auburn University Montgomery where she is responsible for the program courses in Clinical Hematology and Clinical Immunology. She holds a BS degree in Biology as well as a Master’s degree in Adult Education from Troy University. She received her Medical Laboratory Science certificate from St. Margaret’s Hospital School of Medical Technology and will celebrate her 40th year in Laboratory Science this year. Before she became a full-time educator she served in various roles in the clinical laboratory which included five years as a Hematology Supervisor.
 

Keywords

These are the most common topics and keywords covered in Immune Hemolytic Anemias (by LabCE):

immunoglobulins pathologic laboratory antigen-negative non-specifically disease donath-landsteiner medicine discrepancies lupus serum specificities bethesda non-reactive paroxysmal infectious warmer polychromatophilic anti-i reactive alloantibodies blood hematocrit phenotype adsorbed hemoglobin red blood cell hemoglobinemia transfused proceeding vitro drug-induced phenotypes non-immune anemia info rbcs aiha waiha autoadsorbed red blood cells drug-adsorption adsorption adsorb anti-p antigen-antibody drug-antidrug autologous identification penicillin treatment contains transfusions polyspecific considerations intravascular intravenous saline autoadsorptions hemolysis infection newborn rudmann saunders allogeneic autoadsorption procedures erythrocyte button blood bank elution diagnosis transfusion antiglobulin bilirubin transfuse adsorptions autoantibodies hemolytic medication controls drug anemias biphasic sensitizes high-dose titer demonstrable immune clinical plasma globulin fails drug-treated antihuman autocontrol modern indistinguishable antibodies erythematosus amplitude serological warm-reactive anti-igg crossmatches mononucleosis autoimmune cold-reactive reagents alloantibody anti-c3 hemolysin philadelphia body antigens eluate antibody antigen symptoms hemagglutinin harmening davis incubation donor reticulocyte blood banking hemoglobinuria jaundice autoimmunity non-self specificity monospecific autoantibody cells agglutination immune-mediated harvested serologic
How to Subscribe
MLS & MLT Comprehensive CE Package (by LabCE)
Package of 114 online courses$95
Add to cart
Single online course$20
Add to cart
  • Order for instant access through any computer, any browser.
  • No shipping, faxing, or waiting for certificates.
  • Print or save your certificate of completion as soon as you've completed the course.
  • You'll have 90 days to complete your purchased courses.
Course provided by LabCE.
barb-polychro-arrows


case1_autoadsorbedserum


Donath Landsteiner Test


Protein Adsorption


Warm autoimmune.JPG



 
ASCLS CE's design and platform are provided by MediaLab, Inc.