Immune Hemolytic Anemias (by LabCE)

2 P.A.C.E. contact hour(s)

(based on 650 customer ratings)

Author: Erin Tretter, MBA, MT(ASCP)
Reviewer: Kathy W. Jones, MS, MLS(ASCP)CM

Course provided by LabCE.

See more courses in: Blood Banking / Immunohematology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-013-18, approved through 6/30/2020
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Blood Banking / Immunohematology): 2 hour(s)
Course number 20-659548, approved through 9/1/2018

Objectives

  • Compare the different types of immune hemolytic anemias.
  • Identify and investigate potential serologic discrepancies caused by autoimmune and drug-induced hemolytic anemias.
  • Differentiate the four mechanisms involved in drug-induced hemolytic anemias.
  • List medications that may be associated with drug-induced hemolytic anemia.

Customer Ratings

(based on 650 customer ratings)

Course Outline

  • Immune Hemolytic Anemias
      • Introduction
      • Direct Antiglobulin Test (DAT)
      • Classification of Hemolytic Anemias
  • Alloimmune Hemolytic Anemia
      • Alloimmune Hemolytic Anemia
  • Autoimmune Hemolytic Anemias
      • Autoimmune Hemolytic Anemia (AIHA): Introduction
      • Symptoms of Autoimmune Hemolytic Anemias
      • Testing for Autoantibodies
      • Possible Serological and Laboratory Presentations
    • Cold Autoimmune Hemolytic Anemia
      • Cold Autoimmune Hemolytic Anemia
      • Cold Hemagglutinin Disease (CHD)
      • Paroxysmal Cold Hemoglobinuria (PCH)
      • PCH Donath-Landsteiner Test
      • ABO/Rh Typing in the Presence of Cold Autoantibodies
      • Laboratory Presentations of Cold Autoantibodies - Antibody ID and Detection
    • Warm Autoimmune Hemolytic Anemia
      • Warm Autoimmune Hemolytic Anemia (WAIHA)
      • Serological Characteristics in WAIHA
      • WAIHA Investigation: Serological Findings Following Elution
      • Possible Scenarios When Transfusions are Needed in the Presence of WAIHA
      • Detection and Identification of An Alloantibody in the Presence of a Warm-Reactive Autoantibody
      • Autologous Adsorption (Autoadsorption)
      • Allogeneic Adsorption
      • Transfusion Considerations for WAIHA
      • Treatment of WAIHA
    • Mixed-Type Autoimmune Hemolytic Anemia
      • Mixed Type Autoimmune Hemolytic Anemia (AIHA)
  • Drug-Induced Hemolytic Anemia
      • Drug-Induced Immune Hemolytic Anemia Introduction
      • Mechanisms
      • Drug Adsorption Mechanism
      • Immune Complex Mechanism
      • Membrane Modification (Non-Immune Adsorption of Proteins)
      • Induction of Autoimmunity
      • Treatment of Drug-Induced Immune Hemolytic Anemia
      • Laboratory Investigation of Drug-Induced Immune Hemolytic Anemia
  • Case Study
      • Case Study One, continued
      • Case Study One, continued
      • Case Study One, continued
      • Case Study One Conclusion
  • Case Study
      • Case Study Two
      • Case Study Two, continued
      • Case Study Two, Conclusion
  • References
      • References

Additional Information

Author information: Erin Tretter, MBA, MT(ASCP), is currently the Rapid Response Laboratory Supervisor at Paoli Hospital. Erin received her Masters in Business Administration from Florida Institute of Technology where she is a member of the Phi Kappa Phi Honor’s Society. She received her BS in Medical Technology from California University of Pennsylvania and has experience as a Generalist, including Blood Bank, Hematology and Chemistry. Erin is currently the Blood Bank Clinical Instructor for the Clinical Laboratory Science Program at St. Christopher’s Hospital for Children and has 7 years experience teaching immunohematology concepts and laboratory procedures to laboratory science students. She has also taught Blood Bank in the Clinical Laboratory Technician program at the Community College of Philadelphia.
Reviewer information: Kathy W. Jones, MS, MLS(ASCP)CM is currently an Associate Professor in the Medical Laboratory Science Program at Auburn University Montgomery where she is responsible for the program courses in Clinical Hematology and Clinical Immunology. She holds a BS degree in Biology as well as a Master’s degree in Adult Education from Troy University. She received her Medical Laboratory Science certificate from St. Margaret’s Hospital School of Medical Technology and will celebrate her 40th year in Laboratory Science this year. Before she became a full-time educator she served in various roles in the clinical laboratory which included five years as a Hematology Supervisor.
 

Keywords

These are the most common topics and keywords covered in Immune Hemolytic Anemias (by LabCE):

warm-reactive procedures reticulocyte controls harvested serologic hemoglobinemia modern erythematosus saline autoadsorption medicine waiha drug phenotype blood cells donor penicillin harmening aiha anti-i alloantibodies laboratory blood bank red blood cells autoimmunity rudmann hemagglutinin disease adsorptions non-immune cold-reactive autoadsorptions antigen-antibody adsorbed indistinguishable philadelphia non-reactive button immune-mediated infection specificities treatment body hemolytic eluate hematocrit demonstrable bethesda intravenous reactive anti-igg anti-p autoantibodies transfusion contains antigen blood banking medication drug-treated newborn adsorption high-dose plasma immune titer lupus anemia alloantibody antibody serum drug-induced anemias hemolysis polyspecific agglutination antigens antigen-negative hemoglobinuria info autoadsorbed jaundice rbcs incubation antiglobulin adsorb vitro identification hemolysin monospecific red blood cell sensitizes symptoms autoimmune erythrocyte transfuse discrepancies mononucleosis autologous paroxysmal diagnosis globulin elution saunders intravascular reagents non-self antihuman immunoglobulins anti-c3 antibodies transfusions drug-adsorption hemoglobin serological considerations clinical biphasic non-specifically autoantibody bilirubin allogeneic transfused amplitude warmer proceeding crossmatches pathologic autocontrol phenotypes specificity davis drug-antidrug fails polychromatophilic donath-landsteiner infectious
How to Subscribe
MLS & MLT Comprehensive CE Package (by LabCE)
Package of 59 online courses$95
Add to cart
Single online course$25
Add to cart
  • Order for instant access through any computer, any browser.
  • No shipping, faxing, or waiting for certificates.
  • Print or save your certificate of completion as soon as you've completed the course.
  • You'll have 90 days to complete your purchased courses.
Course provided by LabCE.
barb-polychro-arrows


case1_autoadsorbedserum


Donath Landsteiner Test


Protein Adsorption


Warm autoimmune.JPG



 
ASCLS CE's design and platform are provided by MediaLab, Inc.