Laboratory Methods to Aid in the Detection of Sepsis (by LabCE)

1 P.A.C.E. contact hour(s)

(based on 1,005 customer ratings)

Author: Lynne Brodeur, MA, MLS(ASCP)
Reviewer: DeRhonda Crawford, MT(ASCP)

Course provided by LabCE.

This course discusses sepsis and the laboratory tests that are used to detect and intervene in its progression to severe sepsis and septic shock. The usefulness and limitations of C-reactive protein, procalcitonin, and lactic acid concentration are covered in the course. Novel biomarkers that may prove useful as methods for early detection of severe sepsis in the near future are also discussed.

See more courses in: Clinical Chemistry / Urinalysis / Toxicology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-014-17, approved through 2/28/2019
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Clinical Chemistry/UA/Toxicology): 1 hour(s)
Course number 20-547759, approved through 9/1/2018

Objectives

  • Define sepsis, severe sepsis, and septic shock.
  • Explain how C-reactive protein, procalcitonin, and lactic acid are used to aid in the detection and monitoring of sepsis.
  • Explain the mechanisms of C-reactive protein, procalcitonin, and lactic acid.
  • Discuss novel sepsis biomarkers that are currently being researched.

Customer Ratings

(based on 1,005 customer ratings)

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Course Outline

  • Development and Progression of Sepsis
      • Systemic Inflammatory Response Syndrome (SIRS) and Sepsis
      • Severe Sepsis
      • Additional Testing for Diagnosis of Sepsis/Severe Sepsis
      • Septic Shock
      • Sepsis and Bacterial Toxins
  • Laboratory Tests Used in the Detection of Sepsis
      • Biomarkers
      • C-Reactive Protein (CRP)
      • Procalcitonin (PCT)
      • Procalcitonin (PCT) as a Sepsis Biomarker
      • Lactic Acid (Lactate)
      • Lactic Acid (Lactate), continued
  • Mechanisms of C-Reactive Protein, Procalcitonin, and Lactic Acid
      • Mechanism of C-Reactive Protein (CRP)
      • Mechanism of Procalcitonin (PCT)
      • Mechanism of Lactic Acid (Lactate)
      • Other Causes of Increased Lactic Acid (Lactate) Concentration
  • Future Perspectives
      • Increase in Sepsis Cases
      • Novel Biomarkers That Focus on Immunosuppression
  • References
      • References

Additional Information

Level of instruction: Intermediate
Target audience: Medical laboratory scientists, medical laboratory technicians, and MLS students. This course may also be of interest to other health care professionals who are involved in diagnosis and treatment of sepsis. 
Author information: Lynne Brodeur, MA, MLS(ASCP)CM holds a master of arts degree in teaching. She is currently a full time lecturer at the University of Massachusetts Dartmouth and works per diem in Clinical Chemistry at St. Luke's Hospital in New Bedford, MA.
Reviewer information: DeRhonda Crawford, MT(ASCP) is the chemistry supervisor at Gwinnett Medical Center in Lawrenceville, Georgia and the technical supervisor for the Gwinnett Medical Center in Duluth, Georgia. She holds a BS in Medical Technology from the Medical College of Georgia.
Content information: This course discusses sepsis and the laboratory tests that are used to detect and intervene in its progression to severe sepsis and septic shock. The usefulness and limitations of C-reactive protein, procalcitonin, and lactic acid concentration are covered in the course. Novel biomarkers that may prove useful as methods for early detection of severe sepsis in the near future are also discussed. 

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Course provided by LabCE.
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