Osteoporosis and the Clinical Laboratory (by LabCE)

1 P.A.C.E. contact hour(s)

(based on 382 customer ratings)

Author: Lynne Brodeur, MA, MLS(ASCP)CM
Reviewers: Laura Merritt, MS, MT(ASCP); Elizabeth Hart, MA, MLS(ASCP)CM

Course provided by LabCE.

Osteoporosis is the most common metabolic bone disease in the United States. It is a skeletal disease in which the bones become brittle and prone to fracture. This course discusses the clinical background and epidemiology of osteoporosis. Various risk factors as well as signs and symptoms are presented. The traditional screening recommendations along with the current biochemical markers for osteoporosis are discussed in this course.

See more courses in: Clinical Chemistry / Urinalysis / Toxicology

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-112-22, approved through 11/30/2024
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Clinical Chemistry/UA/Toxicology): 1 hour(s)
Course number 20-963670, approved through 11/30/2024


  • Discuss the clinical background of osteoporosis.
  • Discuss the epidemiology of osteoporosis, based on age, sex, race, and other factors.
  • Identify the three types of osteoporosis.
  • Identify the various risk factors for osteoporosis.
  • Describe the signs and symptoms of osteoporosis.
  • List the various screening recommendations established for osteoporosis.
  • Discuss the clinical results.

Customer Ratings

(based on 382 customer ratings)

Course Outline

  • The clinical background of osteoporosis.
      • Clinical Background
    • Bones
      • Function of bones and the role of osteoclasts and osteoblasts
      • Function of bones and the role of osteoclasts and osteoblasts (cont'd)
  • Epidemiology of osteoporosis
      • Epidemiology
      • Epidemiology (cont'd)
      • Epidemiology (cont'd)
      • Male Statistics
  • The Three Types of Osteoporosis
      • Type 1
      • Type 2
      • Type 3
  • Risk factors associated with osteoporosis
      • Gender/ Age and Race
      • Family History and Bone Structure
      • Medications (glucocorticoids)
      • Medications (breast & prostate cancer drugs)
      • Medications (acid reflux)
      • Medications (hormone based)
      • Medications (Anti- Seizure & Diuretics)
      • Medications (other)
      • Smoking
  • Signs and symptoms of osteoporosis
      • Signs & Symptoms
  • Established screening recommendations for osteoporosis
      • Screening Recommendations - Who Should Be Screened
      • Types of Screening
      • FRAX (WHO Fracture Risk Assessment Tool)
      • Gold Standard of Screening
      • BMD (Bone Mineral Density) Interpretation
  • Clinical results
      • Biomarkers of Bone Turnover
      • The "Peptides"
      • TRAP & Osteocalcin
      • Clinical Laboratory Tests and Results
  • References
      • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical laboratory technicians, pathology residents, MLS students, and other health care personnel who have an interest in this subject matter. 
Author information: Lynne Brodeur, MA, MLS(ASCP)CM holds a master of arts degree in teaching. She is currently a full time lecturer at the University of Massachusetts Dartmouth and works per diem in Clinical Chemistry at St. Luke's Hospital in New Bedford, MA.
Reviewer information: Laura L. Merritt MS, MT(ASCP) is the MLT Program Director at Mercyhurst University and also works in a part time capacity as a Medical Technologist at the VA Medical Center in Erie, Pa. She holds a Bachelor degree in Medical Technology from Gannon University in Erie, completing her clinical certificate at St. Vincent’s school of Medical Technology. She also holds a Master’s degree from Mercyhurst University in Erie.
Reviewer Information: Elizabeth Hart, MA, MLS(ASCP)CM is a full-time lecturer at the University of Massachusetts Dartmouth and is also employed in the Transfusion Services Dept. at Brigham and Women's Faulkner Hospital (BWFH) in Boston, MA. She holds a Masters of Arts in Teaching and a Bachelors degree in Clinical Laboratory Science and has been a full-time faculty member in the Dept. of Medical Laboratory Science at UMass Dartmouth since 2003, instructing both lecture and laboratory courses in immunohematology, immunology, and human genetics. At BWFH, she is a senior technologist with 25 years experience in transfusion medicine.

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