Fundamentals of Hemostasis (by LabCE)

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s) Course number 578-111-20, approved through 11/30/2022

Florida Board of Clinical Laboratory Personnel Credit Hours - General (Hematology): 1 hour(s) Course number 20-799032, approved through 9/1/2022

Objectives

• Identify the factors that influence the effectiveness of hemostatic processes.
• Describe the mechanisms that are involved in the arrest of blood flow from a damaged vessel.
• Identify key aspects associated with primary and secondary hemostasis.
• Explain the role of various coagulation components in hemostatic processes.
• Define the extrinsic, intrinsic, and common pathways that are part of the coagulation cascade, identifying the coagulation factors that are associated with each pathway.
• Describe the function of various laboratory tests in evaluating hemostasis.
• Identify common coagulation disorders, their symptomology, and subsequent treatment.
• Explain the role of the prothrombin time and activated partial thromboplastin time in monitoring anticoagulation therapy.

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Course Outline

• An Introduction to the Fundamentals of Coagulation
• An Introduction to the Fundamentals of Coagulation
• An Introduction to the Fundamentals of Coagulation
• An Introduction to the Fundamentals of Coagulation
• Introduction to Primary Hemostasis
• Introduction to Hemostatic Mechanisms
• Introduction to Primary Hemostasis
• Primary Hemostasis – The Vascular System
• Primary Hemostasis – The Vascular System
• Primary Hemostasis – The Vascular System
• Primary Hemostasis – The Vascular System & Platelet Involvement
• Primary Hemostasis – The Vascular System & Platelet Involvement
• Characteristics of the Platelet
• Platelet Function
• Platelet Kinetics
• Summary of Primary Hemostasis
• Overview of Secondary Hemostasis
• Overview of Secondary Hemostasis
• Secondary Hemostasis – Fibrin Formation via the Coagulation Cascade
• Secondary Hemostasis – The Coagulation Cascade
• A Snapshot of the Entire Coagulation Cascade
• Secondary Hemostasis - The Extrinsic Pathway
• Secondary Hemostasis – The Extrinsic Pathway
• Secondary Hemostasis – The Intrinsic Pathway
• Secondary Hemostasis – The Intrinsic Pathway
• Secondary Hemostasis – The Common Pathway
• Secondary Hemostasis – The Common Pathway
• Secondary Hemostasis - Factor Characteristics
• The Fibrinolytic System
• The Fibrinolytic System
• The Fibrinolytic System
• Laboratory Tests of Hemostatic Function
• Basic Laboratory Tests of Hemostatic Function
• Collecting Blood Specimens for Coagulation Testing
• Basic Laboratory Tests of Hemostatic Function (cont.)
• Basic Laboratory Tests of Hemostatic Function – Prothrombin Time (PT)
• Basic Laboratory Tests of Hemostatic Function – Prothrombin Time (PT)
• Basic Laboratory Tests of Hemostatic Function - APTT
• Basic Laboratory Tests of Hemostatic Function – Fibrinogen Assay
• Fibrin/Fibrinogen Degradation Products and D-dimers
• Basic Laboratory Tests of Hemostatic Function - Platelet Function Assay
• Basic Laboratory Tests of Hemostatic Function - Mixing Studies
• Basic Laboratory Tests of Hemostatic Function - Factor Assays
• Coagulation Disorders
• Coagulation Disorders
• Coagulation Disorders - Inherited
• Coagulation Disorders - Inherited
• Coagulation Disorders - Inherited
• Coagulation Disorders - Acquired
• Coagulation Disorders - Acquired
• Coagulation Disorders - Platelet Disorders
• Coagulation Disorders and Liver Disease
• Anticoagulation Therapy
• Anticoagulation Therapy
• Common Anticoagulation Therapy - Heparin Therapy
• Common Anticoagulation Therapy - Oral Anticoagulant Therapy
• References
• References

Additional Information

Level of instruction: Intermediate

Intended Audience: Medical technologists, medical technology students, and those interested in reviewing the fundamentals of coagulation.

Author Information: Carl T. Swithers BSMT (ASCP), CLS (NCA), MBA, is a laboratory examiner with the Pennsylvania Department of Health, specializing in clinical regulatory compliance. A former generalist bench technologist, he also serves as adjunct faculty for an MLT program in Central Pennsylvania.