Bone Marrow Aspiration: Normal Hematopoiesis and Basic Interpretive Procedures (by LabCE)

2 P.A.C.E. contact hour(s)

(based on 300 customer ratings)

Author: Marybeth Helfrich, MT(ASCP)
Reviewer: Paul S. Fekete, MD, FCAP

Course provided by LabCE.

This course provides a thorough review of cellular elements encountered in normal bone marrow. It also provides guidelines for preparation of smears, including an instructional video, and evaluation and reporting of bone marrows.

See more courses in: Hematology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-010-16, approved through 3/31/2018
Course number 20-547599, approved through 9/1/2018

Objectives

  • Describe bone marrow sample collection, smear preparation and routine staining techniques.
  • Recognize and identify myeloid and erythroid precursors found in normal bone marrow aspirates.
  • Compare lymphocytes, hematogones and plasma cells.
  • Compare and contrast monocytes, monocyte precursors and macrophages.
  • Describe benign background cell types found in normal bone marrow.
  • Outline and explain standard procedures for reporting bone marrow differentials.

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(based on 300 customer ratings)

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Course Outline

  • Bone Marrow Aspirates
      • Introduction to Bone Marrow Aspirates and Biopsies
      • Bone Marrow Biopsy
      • Bone Marrow Aspirate and Biopsy Collection
      • Clinical Laboratory's Role: Bone Marrow Aspirates and Biopsies
    • Sample Collection
      • Bone Marrow Collection: Patient Bedside
      • Bone Marrow Delivery
    • Smear techniques
      • Bone marrow Smear Preparation
      • Bone marrow Smear Preparation: Selecting Fragments
      • Long Slide Preparation Techniques: Wedge Smear
      • Long Slide Preparation Techniques: T-prep
      • Long Slide Preparation Techniques: Pull Prep
      • Coverslip Smear Preparation Technique
      • Biopsy Touch Preparation Technique
      • Bone Marrow Smear Techniques Video
    • Routine Staining
      • Manual Staining of Bone Marrow Preparations
      • Manual Staining of Bone Marrow Preparations: Wright's and Wright-Giemsa Stain
      • Automated Stainers
      • Iron Staining
  • Normal Bone Marrow Morphology
      • Bone marrow Differentials
    • Myeloid Maturation Sequence
      • Myeloblast
      • Promyelocyte
      • Myelocyte
      • Myelocytes: Eosinophils and Basophils
      • Metamyelocyte
      • Band Neutrophil
      • Segmented Neutrophil
    • Erythroid Maturation Sequence
      • Erythrocytic Cells: Introduction
      • Pronormoblast (Proerythroblast)
      • Basophilic Normoblast
      • Polychromatophilic Normoblast
      • Orthochromic Normoblast
    • Monocytes / Macrophages
      • Monoblast
      • Promonocyte
      • Monocyte
      • Macrophage (Histiocyte)
      • Hemophagocytosis
    • Lymphocytes / Hematogones / Plasmacells
      • Lymphocyte
      • Hematogone
      • Plasma Cell
    • Megakaryocytes
      • Megakaryocyte: Immature
      • Megakaryocyte: Mature
    • Other Constituents of Normal Bone Marrow
      • Osteoclast
      • Osteoblast
      • Stromal Cells
  • Bone Marrow Evaluation and Reporting
      • Rules for Bone Marrow Differentials
      • Rules for Bone Marrow Differentials, continued
      • Rules for Bone Marrow Differentials, continued
      • Calculating and Reporting the Myeloid:Erythroid (M:E) Ratio
      • Cellularity and Additional Information
      • Responsibility of the Technologist versus Hematopathologist
  • References
      • References

Additional Information

Level of Instruction: Intermediate to Advanced

Intended Audience: Clinical laboratory technologists, technicians, and pathologists. This course is also appropriate for clinical laboratory science students and pathology residents.
 
Author Information: Marybeth Helfrich, MT(ASCP) is currently a Laboratory Technologist Specialist for the Hematology/Oncology Laboratory at Childrens Hospital of Philadelphia. She received her BS, MT from Temple University in Philadelphia and has nearly 40 year experience in both adult and pediatric hematology and oncology settings. She is a regular presenter for ASCLS-PA, has been a presenter for ASCP (local and national), and the Texas Teleconference network. She is responsible for hematology morphology instruction and training for medical technologists and fellows. She is also a regular developer of morphology tutorials for in-house continuing education activities.
 
Reviewer Information: Paul S. Fekete, MD, FCAP is the President and CEO of MediaLab, Inc. He received his MD from Ohio State University and completed his clinical pathology residency at Emory University in Atlanta. He has served as an Assistant Professor of Pathology at Emory and as the Director of Laboratories for Gwinnett Medical Center in Lawrenceville, GA. He is currently Assistant Professor of Pathology, at the Augusta University University of Georgia Medical Partnership. Dr. Fekete is a member of Alpha Omega Alpha Honor Medical Society and a Fellow of the College of American Pathologists.
 
Course information: This course provides a thorough review of cellular elements encountered in normal bone marrow. It also provides guidelines for preparation of smears, including an instructional video, and evaluation and reporting of bone marrows.

Keywords

These are the most common topics and keywords covered in Bone Marrow Aspiration: Normal Hematopoiesis and Basic Interpretive Procedures (by LabCE):

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