Case Studies in Pediatric Hematology (by LabCE)

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s) Course number 578-071-21, approved through 11/30/2023

Florida Board of Clinical Laboratory Personnel Credit Hours - General (Hematology): 1 hour(s) Course number 20-889700, approved through 11/30/2023

Objectives

• Calculate mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and corrected white blood cell (WBC) count.
• Predict peripheral smear microscopic characteristics using basic hemogram parameters.
• Correctly order the sequence of hematopoiesis, beginning with the hematopoietic stem cell.
• Interpret common iron study results and state the blood lead level that currently represents toxicity.
• Recall the diagnostic significance of erythrocyte/zinc protoporphyrin.
• Identify laboratory testing panels that best assess for hematological conditions.
• Categorize cytochemistry stains and immunophenotyping results in the setting of acute leukemias.
• Identify characteristics of macrocytic anemias.
• Define alpha and beta thalassemia and identify key characteristics of each.

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Course Outline

• Approaching “Case Studies in Pediatric Hematology”
• Approaching Case Studies in Pediatric Hematology
• Case 1: Candace, a Four-Week-Old Infant Born Prematurely
• History of Present Illness (HPI) for Candace
• Relevant Laboratory Studies for Candace
• Patient Diagnosis: Anemia of Prematurity
• Review of Hematopoiesis
• Review of Hematopoiesis (continued)
• Case 2: Nicolás, an Eight-Month-Old Born in Mexico
• History of Present Illness (HPI) for Nicolás
• Relevant Laboratory Studies for Nicholás
• Patient Diagnosis: Iron Deficiency Anemia
• Comparing Iron Studies in Iron Deficiency Anemia versus Anemia of Chronic Disease
• Case 3: Patrick, a Five-Year-Old with Stomach Pain
• History of Present Illness (HPI) for Patrick
• Relevant Laboratory Studies for Patrick
• Patient Diagnosis: Lead Poisoning
• Blood Lead Level Collection and Processing Issues
• Case 4: Danielle, a 13-Year-Old Who Is Losing Weight
• History of Present Illness (HPI) for Danielle
• Relevant Laboratory Studies for Danielle
• Patient Diagnosis: Megaloblastic Anemia
• Folic Acid versus Vitamin B12 (Cobalamin) Deficiency
• Case 5: Benton, a 2-Year-Old with "Flu" for a Month
• History of Present Illness (HPI) for Benton
• Relevant Laboratory Studies for Benton
• Patient Diagnosis: Acute Lymphoblastic / Lymphocytic Leukemia (ALL)
• Review of Immunophenotyping and Cytochemistry Staining in Leukemias
• Case 6: Theo, a 12-Month-Old with Dark Urine
• History of Present Illness (HPI) for Theo
• Relevant Laboratory Studies for Theo
• Hemoglobin Structure
• Hemoglobin Structure (continued)
• Patient Diagnosis: Beta Thalassemia Major
• Key Points of Alpha Thalassemia
• Key Points of Beta Thalassemia
• References
• References

Additional Information