Myelodysplastic Syndromes (MDS) (by LabCE)

1 P.A.C.E. contact hour(s)

(based on 311 customer ratings)

George Girgis MLS (ASCP) CM
Reviewers: Margaret Reinhart, MT(ASCP); Leah Coppolino, MPH, MLS(ASCP)CM

Course provided by LabCE.

This course discusses the epidemiology, etiology, and the diagnostic criteria of myelodysplastic syndromes (MDS). The classification of MDS according to the World Health Organization (WHO) guidelines is explained along with morphological features and prognosis of MDS.

See more courses in: Hematology

Included In These Course Packages

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-085-20, approved through 8/31/2022
Course number 20-788174, approved through 9/1/2022


  • Define myelodysplastic syndromes (MDS).
  • Describe the epidemiology and etiology of MDS.
  • Explain the diagnostic criteria of MDS.
  • Describe the morphological features of MDS.
  • Explain the classification of MDS according to the World Health Organization (WHO) guidelines.
  • Discuss prognosis of MDS according to the subtypes (low, intermediate, and high grade MDS).
  • Describe the differential diagnosis of MDS.

Customer Ratings

(based on 311 customer ratings)

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Course Outline

  • Myelodysplastic syndromes (MDS) -- Definition, Etiology, and Epidemiology
      • Definition, Etiology, and Epidemiology
  • Clinical and Diagnostic Features of MDS
      • Clinical Features of Myelodysplastic Syndromes (MDS)
      • Diagnostic Features of MDS
  • The Morphological Features of MDS
      • The Morphological Features of Myelodysplastic Syndromes (MDS)
      • Dysplastic Erythroid Cell Line (Dyserythropoiesis)
      • Examples of Dysplastic Erythroid Cells (Dyserythropoiesis), continued
      • Dysplastic Granulocytic Cell Line (Dysgranulopoiesis)
      • Dysplastic Megakaryocytic Cell Line (Dysmegakaryopoiesis)
  • The Classification of MDS
      • The Classification of Myelodysplastic Syndromes (MDS)
      • The Classification of Myelodysplastic Syndromes (MDS), continued
      • The Significance of Auer Rods in MDS:
  • The Prognostic Criteria of MDS
      • Prognostic Criteria of Myelodysplastic Syndromes (MDS)
  • The Differential Diagnosis of MDS
      • Differential Diagnosis of MDS
  • MDS Therapy
      • MDS therapy
  • References
      • References

Additional Information

Level of instruction: Intermediate

Intended audience: Medical laboratory professionals, clinical laboratory science students, and instructors of hematology.
 Information: George Girgis, MLS (ASCP)CM has over 30 years of experience as a Medical Laboratory Scientist during which he has been a trainer and instructor at Indiana University Health in the field of hematology and hematopathology. George holds a Bachelor of Medicine, Bachelor of Surgery from Ein-Shams University, Cairo, Egypt and a Bachelor of Science in Medical Laboratory Sciences from I.U.P.U.I., Indianapolis, IN.
 Reviewer Information: Margaret Reinhart MS, MT(ASCP) is the MLS Program Director and Senior lecturer in Biological Sciences at the University of the Sciences in Philadelphia PA where she teaches hematology, clinical immunology, parasitology and other related courses. She is also adjunct instructor in Hematology at Pennsylvania Hospital, Philadelphia PA. She holds a Masters Degree in Biology and in Health Care Administration.
 Reviewer Information:  Leah Coppolino, MPH, MLS(ASCP)CM is the Director of Sales at MediaLab, Inc. Previously, she was the Director of the Medical Laboratory Science Program at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania. She holds a Masters in Public Health from Thomas Jefferson University.

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Course provided by LabCE.
Blast with Auer rod

Bone marrow with numerous blasts

Hypogranular & hyposegmented neutrophil


Numerous blasts (MDS-excess blasts)

Sideroblasts ringed

MDS Course Normal Neutrophils

ASCLS CE's design and platform are provided by MediaLab, Inc.