Body Fluid Differential Tutorial (by LabCE)

2 P.A.C.E. contact hour(s)

(based on 1,610 customer ratings)

Author: MaryBeth Helfrich, MT(ASCP)
Reviewer: Paul Fekete, MD, FCAP

Course provided by LabCE.

If you have forgotten the art of differentiating choroid plexus cells from ependymal cells or viral lymphocytes from fluid monocytes, you are in luck! This course provides a thorough morphologic identification of over 40 cell types and disease states to recharge your memory. The course features over 100 crystal clear, perfectly stained body fluid images to illustrate both basic and advanced cellular morphology - perfect for a comprehensive, detailed review which can help refresh any technologist, both in or out of the hematology laboratory. The course is P.A.C.E. approved for 2 full credit hours to help reach your continuing education credit requirements. Enjoy learning and/or reviewing the key identification characteristics of body fluid cells in a user-friendly and fun format. Enroll today!

See more courses in: Hematology

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-016-22, approved through 3/31/2024
Course number 20-904853, approved through 3/31/2024

Objectives

  • Compare and contrast the morphology of cells found in normal cerebrospinal fluid (CSF), normal pleural fluid, normal peritoneal fluid, and normal synovial fluid.
  • Identify the morphology of cells found in bronchoalveolar lavage (BAL).
  • Distinguish abnormal/reactive/infected cell morphology in fluids.
  • Recognize malignant cell morphology in body fluids.
  • Discuss appropriate scenarios for hematology/pathology review.

Customer Ratings

(based on 1,610 customer ratings)

Course Outline

  • Cytocentrifugation Morphology
      • Cytocentrifugation of Body Fluid Samples
  • Cell Types Common To Most Types of Body Fluids
    • Neutrophils
      • Neutrophils
      • Neutrophils, continued
      • Eosinophils vs. Neutrophils
    • Lymphocytes, Atypical Lymphs, Plasma Cells
      • Normal Lymphocytes
      • Lymphocytes
      • Lymphocytes vs. Monocytes
      • Atypical Lymphocytes vs. Monocytes
      • Lymphocytes and Atypical Lymphocytes
      • Atypical Lymphocytes
      • Viral Lymphocytes
      • Lymphocytes and Plasma Cells in Body Fluids
    • Monocytes and Macrophages
      • Monocytes
      • Monocytes vs Lymphocytes
      • Monocytes and Macrophages
      • Macrophages
      • Phagocytosis
      • Hemosiderin
      • Histiocytes
  • Cells Found in Cerebrospinal Fluid
    • Cerebrospinal Fluid: Non-Blood Cells
      • Ependymal Cells
      • Ependymal Clumps
      • Choroid Plexus Cells
    • Cerebrospinal Fluid: Bone Marrow Contamination
      • Bone Marrow Contamination in CSF
  • Cells Found in Pleural and Peritoneal Fluids
    • Mesothelial cells
      • Mesothelial Cells
      • Mesothelial Cells, continued
      • Reactive Mesothelial Cells
  • Cells Found in Synovial Fluids
      • Synovial Lining Cells
      • Synovial Lining Cells, continued
  • Cells Found in Bronchoalveolar Lavages
    • Bronchial Lining Cells
      • Bronchial Lining Cells
      • Bronchial Lining Cells, continued
  • Infectious Organisms in Body Fluids
      • Infectious Organisms in Body Fluids
    • Bacteria
      • Intracellular and Extracellular Bacteria
      • Intracellular Bacteria
      • Peritoneal Lavage Trauma
      • Trauma STAT
      • Septic Arthritis
    • Fungus
      • Yeast
      • Candida albicans - Germ Tube Formation
      • Hyphae
    • Toxoplasma
      • Central Nervous System (CNS) Toxoplasmosis
      • Central Nervous System (CNS) Toxoplasmosis, continued
  • Malignant Fluids with Leukemia and Lymphoma.
      • Leukemic Fluids
    • Lymphoid Leukemia / Lymphomas
      • Acute Lymphoblastic Leukemia (ALL): L1 Morphology
      • Central Nervous System (CNS) Relapse: L2 Acute Lymphoblastic Leukemia (ALL)
      • Burkitt Lymphoma
      • Non-Hodgkin Lymphoma
      • Anaplastic Large Cell Lymphoma (ALCL)
    • Myeloid Leukemias
      • Acute Myeloid Leukemia (AML)
      • Acute Myeloid Leukemia (AML), continued
      • Acute Monoblastic Leukemia (AMoL)
  • Malignant Fluids with Metastatic Tumor
      • Metastatic Tumors in Fluid Cytospins
      • Adenocarcinoma in Peritoneal Fluid
      • Alveolar Rhabdomyosarcoma (ARMS) in Pleural Fluid
      • Atypical Teratoid/Rhabdoid Tumors (ATRT) in Cerebrospinal Fluid
      • Metastatic Melanoma in the Cerebrospinal Fluid (CSF)
      • Primitive Neuroectodermal Tumor (PNET) in Cerebrospinal Fluid
      • Medulloblastoma in Cerebrospinal Fluid
      • Neuroblastoma in Pleural Fluid
      • Neuroblastoma Tumor Clump vs. Mesothelial Cells in Pleural Fluid
      • Retinoblastoma in Cerebrospinal Fluid
  • References
      • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: This course is intended for laboratory professionals who have experience with peripheral blood morphology and basic experience with body fluid differential analysis.  This tutorial will provide a review of normal and abnormal body fluid morphology utilizing Wright-Giemsa stained cytospin preparations from cerebrospinal fluid (CSF), pleural, peritoneal and synovial fluids as well as bronchial alveolar lavage (BAL) samples.
Author Information: Marybeth Helfrich, MT(ASCP) is currently a Laboratory Technologist Specialist for the Hematology/Oncology Laboratory at Children's Hospital of Philadelphia. She received her BS, MT from Temple University in Philadelphia and has nearly 40 years of experience in both adult and pediatric hematology and oncology settings. She is a regular presenter for ASCLS-PA, has been a presenter for ASCP (local and national), and the Texas Teleconference network. She is responsible for hematology morphology instruction and training for medical technologists and fellows. She is also a regular developer of morphology tutorials for in-house continuing education activities.
Reviewer Information: Paul Fekete, MD, FCAP is the President and CEO of MediaLab, Inc. He received his MD from Ohio State University and completed his clinical pathology residency at Emory University in Atlanta. He has served as an Assistant Professor of Pathology at Emory, the Director of Laboratories for Gwinnett Medical Center in Lawrenceville, GA., and President of Gwinnett Pathology Associates.  Dr. Fekete is a member of Alpha Omega Alpha Honor Medical Society and a Fellow of the College of American Pathologists.

Keywords

These are the most common topics and keywords covered in Body Fluid Differential Tutorial (by LabCE):

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