Metabolic Syndrome (by LabCE)

1 P.A.C.E. contact hour(s)

(based on 478 customer ratings)

Author: Mary Ellen Koenn, MS, MT(ASCP), CLS(NCA)
Reviewer: Leslie Lovett, MS, MT(ASCP) and Alexandru Casapu, MBA, MLS(ASCP)CM, PBTCM

Course provided by LabCE.

This course discusses the metabolic syndrome, a diagnosis that is not associated with one particular disease, but rather the probability of developing certain diseases or disorders as a result of a combination of defined risk factors. Explanations are presented about the inter-relationship between cytokines produced by adipose tissue and metabolic syndrome risk factors. Laboratory tests that are used to detect and monitor metabolic syndrome are also discussed.

See more courses in: Clinical Chemistry / Urinalysis / Toxicology

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-068-21, approved through 10/31/2023
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Clinical Chemistry/UA/Toxicology): 1 hour(s)
Course number 20-863993, approved through 10/31/2023


  • Identify the risk factors for metabolic syndrome.
  • List other diseases and medical complications associated with metabolic syndrome.
  • Describe the impaired lipid metabolism that occurs in metabolic syndrome and how it affects carbohydrate metabolism and produces an atherogenic dyslipidemia.
  • Explain the role of insulin resistance and obesity in the onset of metabolic syndrome.
  • Describe the role of the laboratory in diagnosis and monitoring patients diagnosed with metabolic syndrome.
  • Interpret patient information and laboratory results using the NCEP: ATP III metabolic syndrome criteria and laboratory reference ranges.
  • Describe clinical treatment goals in metabolic syndrome.

Customer Ratings

(based on 478 customer ratings)

Course Outline

  • Metabolic Syndrome
      • Metabolic Syndrome
      • Insulin Resistance
      • The Importance of Diagnosing Metabolic Syndrome
      • Risk Factors
      • Dyslipidemia
      • Atherogenic Dyslipidemia
      • Hypertension
  • Adipose tissue and metabolic syndrome
      • Adipokines Significant to Insulin Resistance and Metabolic Syndrome
      • TNF-alpha
      • Interleukin-6 (IL-6)
      • Plasminogen Activator Inhibitor-1 (PAI-1)
      • Adiponectin
      • Angiotensinogen
      • Leptin
      • Resistin
  • Medical Conditions Associated with Metabolic Syndrome
    • Type 2 Diabetes
      • Metabolic Syndrome and Type 2 Diabetes
    • Cardiovascular Disease
      • Atherosclerosis
      • Adipokines and Atherosclerotic Inflammatory Process
      • Endothelial Dysfunction
    • Prothrombotic State
      • Prothrombotic State
    • Other Possible Medical Conditions
      • Medical Complications of Metabolic Syndrome
  • Diagnosis of Metabolic Syndrome
      • Variation in Diagnostic Criteria
      • Adult Treatment Panel III and ACC/AHA Guidelines
      • NCEP: ATP III Diagnostic Criteria for Metabolic Syndrome
  • Clinical Management in Metabolic Syndrome
      • Treatment
      • Magnesium, Calcium, and Vitamin D
  • Laboratory Role in Metabolic Syndrome
      • Clinical Laboratory Testing in Metabolic Syndrome
  • References
      • References

Additional Information

Level of instruction: Intermediate
Intended Audience: Clinical laboratory technologists and technicians, and other health care personnel who have an interest in this subject matter. This course is also appropriate for clinical laboratory science students and pathology residents.
Author information: Mary Ellen Koenn, MS, MT(ASCP), CLS(NCA) is an associate professor at West Virginia University School of Medicine in the Medical Technology Program. During her career as a medical technologist and educator, she has been a laboratory supervisor and manager and has held several teaching positions. She is active in the American Society for Clinical Laboratory Science (ASCLS), resulting in a nomination as ASCLS Member of the Year in 2006. She is also a member of the American Association for Clinical Chemistry. She is the author of numerous articles for laboratory publications and textbook chapters and is a frequent presenter at laboratory seminars and workshops. Ms. Koenn holds a Master of Science degree in Medical Technology.
Reviewer information: Leslie Lovett, MS, MT(ASCP) is the Clinical Education Coordinator of the Medical Laboratory Technology Program and a professor at Pierpont Community and Technical College in West Virginia.  She holds a MS degree in Medical Technology with classes toward a PhD in Pharmacology and Toxicology.
Reviewer Information: Alexandru Casapu, MBA, MLS(ASCP)CM, PBTCM has over 20 years of experience as a medical laboratory scientist, section supervisor, and laboratory manager. He is the former Director of Clinical Laboratory Technology Program at Georgia Piedmont Technical College. He is currently a Program Director at MediaLab, Inc. Alexandru holds BS degrees in Biology and Medical Technology from Clark Atlanta University and a MBA from the University of Georgia.

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